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  • On September 26, UCLA researcher reported the results of a study, which indicated that Asians who will be struggling with alcoholism may benefit especially from naltrexone, one of three medications licensed by the U.S. Food and Drug Administration (FDA) for the treatment of alcoholism. Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation which makes them likely to benefit from naltrexone, in comparison with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are presently available online ( inside journal Neuropsychopharmacology and will be published in an upcoming print edition from the journal.

    Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you should err on the side of caution and allow FDA do its job and demand some investigation be done so your public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on the medications.

    Researchers discovered that participants using this drug for the year, dropped a few pounds within 4 weeks and have kept the weight off throughout the 56 weeks in the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them far better and safer.

    Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that at the time of right now there are no long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA.

    Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug also can raise blood pressure levels and heartbeat, and must not be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.

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