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    Researchers found that participants taking this drug to get a year, lost weight within four weeks and have kept the extra weight off throughout the 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which might make them more potent and safer.

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    Seizures really are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise hypertension and heartrate, and really should not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise hypertension and heart rate and must stop used in patients with uncontrolled high hypertension, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

    Other people who should avoid using Contrave are patients struggling with bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave shouldn't be prescribed for females who are pregnant or trying to become pregnant.

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