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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight loss in addition to a reduced-calorie diet and exercise.

    Using two separate drugs to lose weight naturally can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it one should err along the side of caution and let the FDA do its job and demand some research be done so that the public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on their own medications.

    Researchers found that participants taking this drug for the year, lost weight within four weeks and have kept the load off during the entire 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, that might make them far better and safer.

    Combo-pilling may be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is now popular will be the fact that at the time of right now there aren't any long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.

    Seizures can be a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure level and heartbeat, and really should not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high hypertension, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    Acamprosate also activly works to eliminate the wish to drink through the elimination of the the cravings for having a drink. The major difference between Naltrexone and Acamprosate is always that Acamprosate is just not yet accessible in the United States. While it continues to be widely studied in Europe the complete chemical reason that it works remains unknown. It is considered that it disturbs receptors within the brain which process glutamate, which in effect alters the best way ones body reacts to alcohol intake. Several of the European research has shown a lot of promise with Acamprosate for the reason that some of the patients had a practically double rate of success for staying sober.

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