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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight management in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to lose weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err on the side of caution and allow the FDA do its job and demand some research be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on their medications.

    Researchers discovered that participants using this drug for the year, dropped excess weight within a month and have kept the extra weight off during the entire 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs that are made up of several active ingredient, which may make them far better and safer.

    Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that since right now there are not any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.

    Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise hypertension and heartrate, and mustn't be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure levels, along with by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients on the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

    "This may be the first drug I'm aware of that targets the appetite and reward centres in the brain," he explained.

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